Research library / Compounds

What is ?

A large synthetic peptide built to act on several hormone receptors at once.

is a large synthetic peptide designed to activate several related hormone receptors with a single molecule, a type of compound researchers call a multi-receptor agonist. Its developer first described it in 2022. Prism Labs supplies it as a lyophilized vial.

01

What it is

It is one modified peptide chain, not a blend of separate peptides. The reference record lists the formula C221H342N46O68 and a molecular weight of about 4,731 g/mol (PubChem CID 171934787).

That mass is several times that of most catalog peptides, and the chemical modifications mean a sequence alone does not identify it. The identity result on the COA, a measured mass, is what confirms a lot.

Sources: [1] PubChem · reference structure

02

Where it came from

It was described in 2022 in a paper that covered its design, its activity at three receptors in cell assays, studies in mice and a first single-dose study in people.

A larger phase 2 study followed in 2023. Compared with older catalog peptides, its literature is young and comes mostly from its developer’s program.

An older relative in the catalog is , first described in 2018. It is designed to activate two related hormone receptors; is designed to activate three, the same two plus a third. They are separate molecules with different masses: What is ?

Sources: [2] Cell Metabolism · 2022 · [3] New England Journal of Medicine · 2023 · [5] Molecular Metabolism · 2018

Every lot ships with its own certificate of analysis.

03

What researchers have studied

Published work falls into two groups:

  • Receptor pharmacology: how strongly it activates each of its three target receptors in cell assays.
  • Animal and clinical studies from the developer’s program.

Because the compound is young, read each paper for its model and measurements rather than relying on summaries.

These are observations in laboratory models. They are not evidence about any use in people.

Sources: [2] Cell Metabolism · 2022 · [3] New England Journal of Medicine · 2023

04

Why identity testing matters for large peptides

Longer chains give synthesis more places to go wrong: missing or extra amino acids, protecting groups that were not fully removed, and other related impurities. A 2014 review catalogs them.

HPLC purity shows how much of the sample is the main product; mass spectrometry shows whether that product has the right mass. For a peptide this size, read both results.

Sources: [4] Journal of Pharmaceutical and Biomedical Analysis · 2014

05

How it is supplied and stored

ships as a lyophilized (freeze-dried) powder in 20 mg or 30 mg vials. The powder is stable at room temperature in transit. For lab use it is reconstituted with bacteriostatic water such as .

Concentration is content divided by volume: 20 mg in 2 mL gives 10 mg per mL. The reconstitution calculator handles other combinations.

For storage before and after reconstitution, see how to store lyophilized peptides.

06

How to verify a batch

Every lot has its own certificate of analysis from an independent lab. Read three results separately:

  • Identity: confirms the expected compound was detected.
  • Purity: the share of the measured material that is the intended compound.
  • Content: the amount measured, compared with the label.

Then match the lot number on your vial or bottle to the report, and use the report’s verification link to confirm it with the testing lab. Step by step: how to read a peptide COA.

A little more clarity

Questions, answered

What is ?

A large synthetic peptide designed to activate several related hormone receptors at once. Its developer first described it in 2022.

Is a peptide?

Yes. It is a single modified peptide chain of about 4,731 g/mol, not a blend.

What sizes and formats are available?

20 mg and 30 mg lyophilized vials. Each lot has its own COA.

How do I confirm what is in a vial?

Read the identity result on the lot’s COA, which reports the measured mass, and match the lot number to the report. Step by step: how to read a peptide COA.

Is it for human use?

No. Prism Labs sells it for laboratory research use only.

Follow the evidence

Sources & reading notes

Open the original record for its methods and limitations. The sources below do not certify the supplied product or its finished formulation.

  1. PubChem · reference structure ↗

    The covalent peptide structure referenced in the product specifications, excluding counter-ions; not a batch measurement.

  2. Cell Metabolism · 2022 ↗

    The developer’s discovery paper: cell, mouse and first human data.

  3. New England Journal of Medicine · 2023 ↗

    Phase 2 clinical study.

  4. Journal of Pharmaceutical and Biomedical Analysis · 2014 ↗

    Review of impurities that arise in synthetic peptides.

  5. Molecular Metabolism · 2018 ↗

    Discovery paper for the two-receptor compound compared in this article.

Prepared by Prism Labs from the linked source records and public product documentation. Research context only; not a preparation protocol or a claim about outcomes. Send a source correction.

From reading to verification

Match the material to its record.

Check the product, size and lot. Then read identity, purity and measured content as separate results.